Project information

The Netherlands X-omics Initiative is a  new facility as part of the National Roadmap for Large-Scale Research Infrastructures. It is partly funded by NWO with a total budget of 40 million euro. The project started on September 2018 and will last for ten years.

The project aims to establish a X-omics research infrastructure across the Netherlands consisting of several existing facilities with various expertise’s related to molecular biology research (genomics, proteomics, metabolomics and data integration & analysis).

Through the project, we will:
1. Advance X-omics technologies far beyond state-of-art,
2. Realize an integrated X-omics infrastructure in the Netherlands.

Access will be provided to these facilities to enable researchers to use the newest X-omics technologies in their projects and drive new insights in biology.

helpdesk will be created through which researchers can get into contact with our experts for advice on X-omics approaches in general or specific omics-related sample or data analysis challenges.

During the project, training schools will be set up with courses on X-omics approaches and several meetings will be organized to expand the Dutch X-omics community.

A proof of principle of the X-omics approach will be provided by starting 3 technological demonstrators on different levels (cellular, individual and population).

In our brochure you will find information about:

  • The research infrastructure 
  • X-omics equipment and its services 
  • The helpdesk 
  • Training & events 
  • Our X-omics community 

Access to this infrastructure, its available equipment and services is possible for all researchers by contacting the X-omics helpdesk. 


We will demonstrate the added value of our X-omics approach at 3 levels of biomedical research: the cellular, individual and population level.

Examples of research questions that can be addressed are:


  • How does the metabolism of a single cell change during differentiation?
  • How do cells influence each other’s function?
  • How does a cell respond to cancer drugs or become drug resistant?
  • How do dynamic signaling pathways change in time?


  • What changes molecularly when a person gets sick?
  • What molecular features are shared by rare disease patients?
  • How does the molecular system of a person respond to a biological or pharmaceutical challenge?
  • How similar are phenocopies in health/disease at the molecular level?


  • How can we better understand health and disease?
  • How can we better understand the functional consequences of genetic diversity?
  • How do environmental events affect a population’s molecular system?
  • How can we best translate molecular population data to new screening tools?
NWO logoThis research was (partially) funded by NWO, project 184.034.019