Welcome to the website of the Netherlands X-omics Initiative!
On this website, you will find information and regular updates on the latest developments, results and activities of the project.
The departments Center for Molecular and Biomolecular Informatics (CMBI), Translational Metabolic Laboratory (TML) and Human Genetics organized a successful Radboud summerschool on “Integrative X-omics Analyses Empowering Personalized Healthcare”. The course coordinators Prof. Alain van Gool and Prof. Peter-Bram ‘t Hoen are looking back at an exciting week, in which 20 participants from all over Europe convened for a week full of lectures, practicals, and labtours.
The week started with an introduction into biomarkers for personalized healthcare by Alain van Gool (TML). Marcel Nelen (Human Genetics) introduced them into novel genomics technologies, and Hans Wessels and Jolein Gloerich (TML) did the same for novel proteomics technologies. Peter-Bram ‘t Hoen presented a range of X-omics data integration strategies. Other topics like metabolomics, methylation and network-based data integration were covered by external speakers from the Netherlands X-omics Initiative.
Throughout the week, the participants worked on an assignment for which they needed to design a X-omics study, and define a data analysis and management plan. The participants worked in multidisciplinary teams of four. Their different scientific backgrounds helped to address this assignment form different angles. On Friday, the participants presented their exciting studies covering a range of different topics:
The organizers are looking forward to a next edition.
More information about the program click here.
The Netherlands X-omics Initiative is a National Roadmap Large-Scale Research Infrastructure, partially funded by NWO with a total budget of 40 million euro.
X-omics aims to realise the next generation 'omics' infastructure across the Netherlands, by combining technologies in the field of genomics, proteomics, metabolomics and data analysis, integration & stewardship.
This infrastucture will be accessible to all researchers. To allow communication between the users of the infrastucture a X-omics community will be established.
This community will interact via:
● News letters
● Social media
The Handbook of Biomarkers and Precision Medicine was published May 1, 2019.
Several members of the X-omics consortium have been involved in the creation of this handbook:
The handbook provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development.
Revenues (of the X-omics consortium members) will go to charities for new translational biomarker research.
For more information and to order this handbook visit the following link.
During the Benelux Precision Medicine Forum on May 13-14 2019 in Utrecht, several consortium members of the Netherlands X-omics Initiative were present as speakers, with presentations and posters. For example:
For more information about the Precision Medicine Forum events click here.
At the opening event of the Netherlands X-omics Initiative, Bruker and the Translation Metabolic Laboratory (TML) at Radboud University Medical Center (UMC) jointly announced the establishment of a Center of Excellence (CoE) for Translational Omics. Under the leadership of Professor Alain van Gool, the joint CoE will focus on clinical translation of innovative metabolic profiling using various Omics approaches. The collaboration will center around the development of 4D omics methods using the timsTOF Pro ultra-high sensitivity, trapped ion mobility quadrupole time-of-flight mass spectrometer that was recently acquired by the TML.
For more information about the establishment please see the following link.
X-omics festival: "The future is now! ", @Nijmegen, April 16th 2019.
The X-omics consortium will organise a X-omics festival in Nijmegen on April 16th 2019. The festival is the official kick off of the X-omics project and will contain several elements:
The program is available below. Registration is closed (and required to attend this meeting).
We hope to meet you in Nijmegen!
X-omics project management team.
During the HEALTH-RI conference 2019 on January 17th, several partners of the Netherlands X-omics initiative were present as chairs of sessions, with presentations and posters. For example:
For the X-omics project management team this was the first occasion to present the project to the public and explain what the project is about. A lot of interested people and fruitful discussions!
Photo: Edwin Cuppen during his presentation. Made by Thijs Rooimans.
Data scientist / Postdoctoral researcher X-omics
Within the contexts of the national large-scale X-omics research infrastructure (coordinated by prof. A. van Gool, Radboudumc) and the European Joint Programme on Rare Diseases (EJPRD, coordinated by dr. Julkowska, Inserm, Paris), we are looking for an ambitious data scientist, who develops data analysis and integration approaches for large-scale -omics data and is dedicated to the introduction of these approaches in personalized health care. The candidate is committed to the counselling and training of biomedical researchers in these computational approaches. The candidate will contribute to the realization of a digital research environment (DRE) where these computational approaches can be applied and which contributes to the Findability, Accessibility, Interoperability and Reusability (FAIRness) of data, tools and services.
The Netherlands X-omics Initiative will establish a central helpdesk to provide access to the X-omics research infrastructure and its respective facilities.You can contact the helpdesk assistant for: