Welcome to the website of the Netherlands X-omics Initiative! 

On this website, you will find information and regular updates on the latest developments, results and activities of the project.​

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The Netherlands X-omics Initiative is a National Roadmap Large-Scale Research Infrastructure, partially funded by NWO with a total budget of 40 million euro.

X-omics aims to realise the next generation 'omics' infastructure across the Netherlands, by combining technologies in the field of genomics, proteomics, metabolomics and data analysis, integration & stewardship.

This infrastucture will be accessible to all researchers. To allow communication between the users of the infrastucture a X-omics community will be established. 

This community will interact via:
● Meetings
● News letters
● Social media

If you would like to join the X-omics community, please send an e-mail to: This email address is being protected from spambots. You need JavaScript enabled to view it. 


The Handbook of Biomarkers and Precision Medicine was published May 1, 2019.

Several members of the X-omics consortium have been involved in the creation of this handbook:

  • Alain van Gool (coordinator of X-omics) and Mark Fidock (SAB member of X-omics) are editors of this handbook.
  • X-omics consortium members Edwin Cuppen, Theo Luider and Rainer Bischoff have contributed to this handbook.

The handbook provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development.

Revenues (of the X-omics consortium members) will go to charities for new translational biomarker research.

For more information and to order this handbook visit the following link.

Handbook of Biomarkers and Precision Medicine


During the Benelux Precision Medicine Forum on May 13-14 2019 in Utrecht, several consortium members of the Netherlands X-omics Initiative were present as speakers, with presentations and posters. For example:

  • Alain van Gool organised a workshop with the title 'X-omics to gain new insights and advance Precision Medicine' and also gave a lecture about 'Translational X-omics diagnostics to drive Personalized Healthcare'.
  • Peter-Bram t’Hoen gave a lecture with the title; “Data Integration: Overcoming the Challenges of Integrating Large Volumes of Complex Data from Heterogeneous Sources”.
  • Albert Heck gave a lecture with the title: “Proteomics: Towards Personalized Proteome Profiling”.
  • Thomas Hankemeier gave a lecture with the title: “Metabolomics: Developing Strategies for Metabolomics-Driven Systems Biology to Enable Personalised Medicine”.
  • Cisca Wijmenga joined the panellist of expert speakers during the presentation “Exploring the Future Direction of Precision Medicine: What We Hope to Achieve and Required Next Steps”.

For more information about the Precision Medicine Forum events click here.


At the opening event of the Netherlands X-omics Initiative, Bruker and the Translation Metabolic Laboratory (TML) at Radboud University Medical Center (UMC)  jointly announced the establishment of a Center of Excellence (CoE) for Translational Omics. Under the leadership of Professor Alain van Gool, the joint CoE will focus on clinical translation of innovative metabolic profiling using various Omics approaches. The collaboration will center around the development of 4D omics methods using the timsTOF Pro ultra-high sensitivity, trapped ion mobility quadrupole time-of-flight mass spectrometer that was recently acquired by the TML.

For more information about the establishment please see the following link.


The world-wide Metabolomics 2019 conference will take place in The World Forum in The Hague from June 23-27th 2019. Four members of the X-omics consortium are part of the local organisation:

• Thomas Hankemeier
• Merlijn van Rijswijk
• Cornelia van Duijn
• Eline Slagboom

The conference will highlight applications of metabolomics as well as the latest technological developments, including X-omics approaches. Prior to the conference there will be 20 workshops offering a great learning opportunity for early career scientists.

Registration is now open (early bird registratrion with a significant discount is still possible!). Abstracts for oral presentations can be submitted until March 31st 2019. The organisation encourages all researchers developing and applying metabolomics in their research to send in an abstract for an oral presentation or poster.

The X-omics consortium will also be present at the Metabolomics 2019 conference with a keynote speaker (D. Boomsma), several lectures and a booth (number T32).

During the Metabolomics 2019 conference, vacancies for X-omics will be presented at the career night on sunday evening, June 23rd.

For more information and registration, visit the Metabolomics 2019 website.


Integrative X-omics analyses empowering personalized healthcare, 1-5 July 2019.

In this course you will receive high profile lectures and practical training on the integrated use of molecular-omics technologies in personalized prevention, diagnostics and treatment, to optimize your experimental and analysis strategies.

For more information about this course and to apply please visit the Radboud Summer School website.

Flyer X-omics Summer School 2019

X-OMICS FESTIVAL (event is finished)

X-omics festival: "The future is now! ", @Nijmegen, April 16th 2019.

The X-omics consortium will organise a X-omics festival in Nijmegen on April 16th 2019. The festival is the official kick off of the X-omics project and will contain several elements:

•X-omics project kick off
•Keynote lectures (learn about the X-omics approach​!)
•Meet & greet with the experts
•Live Q&A
•Technology demonstrations
•Sharing of dreams & visions
•Networking opportunities

The program is available below. Registration is closed (and required to attend this meeting).

We hope to meet you in Nijmegen!

Kind regards,
X-omics project management team.

Program X-omics festival 16 April 2019 (updated 18 March 2019)

Bioke logo new sharing outlines HighRes LOGO CMYK new olink logo 2017   TFS logo cmyk ezPacBio ShortLogo color RGBWaters logo black 1ONT logo PMS    Bruker logo rgb 300dpiSCIEX LOGO RGB

During the HEALTH-RI conference 2019 on January 17th, several partners of the Netherlands X-omics initiative were present as chairs of sessions, with presentations and posters. For example:

  • ·The coordinator of X-omics, Alain van Gool(Radboudumc) chaired a session in the P4 theme “Prevention” with the title “Individuals are given tailored tools to prevent disease development”.
  • ·X-omics partner Gerrit Meijer(NKI) chaired a parallel session within the same P4 theme; “Optimizing the wellness of individuals by predicting disease and delivering personalized treatments”
  • ·One of the X-omics core team members Edwin Cuppen(UMCU - Hartwig Medical Foundation) gave a presentation: “Tumor whole genome sequencing for personalized cancer treatment”.
  • ·Posters from several partners such as BBMRI-NL, Surf and UMCG/RUG were presented, for example P18, P43, P44 and P45 (see abstract book for more details: https://www.health-ri.org/abstractbook-2019)

For the X-omics project management team this was the first occasion to present the project to the public and explain what the project is about. A lot of interested people and fruitful discussions!

Health RI meeting

Photo: Edwin Cuppen during his presentation. Made by Thijs Rooimans.


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Data scientist / Postdoctoral researcher X-omics

Within the contexts of the national large-scale X-omics research infrastructure (coordinated by prof. A. van Gool, Radboudumc) and the European Joint Programme on Rare Diseases (EJPRD, coordinated by dr. Julkowska, Inserm, Paris), we are looking for an ambitious data scientist, who develops data analysis and integration approaches for large-scale -omics data and is dedicated to the introduction of these approaches in personalized health care. The candidate is committed to the counselling and training of biomedical researchers in these computational approaches. The candidate will contribute to the realization of a digital research environment (DRE) where these computational approaches can be applied and which contributes to the Findability, Accessibility, Interoperability and Reusability (FAIRness) of data, tools and services.

For more information about this vacancy please click here.


Our Helpdesk

The Netherlands X-omics Initiative will establish a central helpdesk to provide access to the X-omics research infrastructure and its respective facilities.

You can contact the helpdesk assistant for:
  • Expert assistance to help design your X-omics experiments.
  • Analyses of samples in 1 of the facilities (the assistant can refer you to the right facility).
  • For general information about the X-omics project.
  • For information on specific activities such as the training schools or events organized by the consortium.

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This research was (partially) funded by NWO, project 184.034.019