The Netherlands X-omics Initiative (X-omics, pronounce as CROSS-omics) is a National Roadmap Large-Scale Research Infrastructure, partially funded by NWO with a total budget of 40 million euro. The project started September 2018 and will last for 10 years.

X-omics aims to establish a X-omics research infrastructure across the Netherlands, by combining technologies in the field of genomics, proteomics, metabolomics and data analysis, integration & stewardship. With this infrastructure biomedical problems can be solved using an integrated approach (analysis of samples using the available omics technologies of the infrastructure).

Two major goals are:
1. Advance X-omics technologies far beyond state-of-art,
2. Realize an integrated X-omics infrastructure in the Netherlands.

A central helpdesk has been created to provide access to the research infrastructure and enable researchers to use the newest X-omics technologies in their projects. Via this helpdesk researchers can get into contact with X-omics experts for advice on X-omics approaches.

A proof of principle of the X-omics approach will be provided by starting 3 demonstrator projects on different levels (cellular, individual and population).

During the project, training schools will be set up for new ‘omics’ users and for ‘omics’ practitioners.

To allow communications between the users of the infrastructure a X-omics community will be established. This community will interact via meetings, newsletters and social media.