METABOLOMICS
Recently, metabolomics has demonstrated it can capture the cumulative effect of the environment on health and disease. It can therefore ideally complement genomics to assess someone’s health status and predict the onset of diseases. So far, there is not 1 generic method to capture the diverse and complex metabolome due to the large variation of physicochemical properties and concentration of metabolites present in biological samples. Therefore, a combination of metabolic profiling methods is often used and a proper study design is important to answer a biological question.
To use metabolomics to detect the onset of diseases, reveal disease mechanisms and choose the proper prevention and treatment strategy, X-omics will address the following main challenges:
Higher throughput, lowering costs and amount of sample needed to enable population-based metabolomics analyses.
Absolute quantitation for more metabolites enabling the combination of different studies and additional data analysis strategies such as fluxomics.
Miniaturizing metabolomics technology to enable analysis of organoids, organ-on-a-chip and single cell samples.
Developing technologies to study the dynamics within and between cells and tissues and the human body.
Metabolomics servics
