GENOMICS
While next-generation DNA sequencing technologies are now widely accessible and commonly used for many genome analyses and tag-based approaches, clear technological challenges remain. One of the difficulties is the growing capacity demand and sustaining the growing application of genomics in biomedical research will require that data interpretation becomes as accessible as data generation. Increased reproducibility through the adoption and implementation of a FAIR framework, together with increased throughput, will spur the progress of genomics.
There are currently three main challenges that X-omics will focus on to efficiently advance genomics by achieving new breakthroughs:
Higher throughput, lowering costs and sample needed to improve scaling of whole genome sequencing analysis and tag-based approaches.
Higher accuracy and sensitivity for e.g. structural variant detection using long-read technology.
Improve coverage of analysis towards more complete (human) genomes and transcriptomes.
